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When it comes to designing novel drugs, achieving specificity is a major challenge. An effective drug must bind tightly to its target protein while avoiding unwanted side effects that can result from…
Hello everyone, I wanted to apologize for the recent server issues. The migration brought unforeseen challenges, particularly with DNS changes. As a newcomer to server management and BOINC projects, I've been on a steep learning curve to transition this project to a new server. As mentioned in a previous post, and reiterated here, we have set up a temporary DNS entry for milkyway-new that now points to the server. The changes will take some time to become effective (I don't have a specific…
G proteins are essential molecular players in the intricate symphony of cellular signaling. From our vision to our sense of smell, neurotransmission to cell growth, G proteins are at the core of…
Hello everyone, We are preparing to migrate MilkyWay@home to a new server on 1 November 2023 at 2 pm UTC. This new server has better hardware (specifically more memory), which we expect will improve the performance of the website and the rate at which you can get new workunits. We are forced to perform this migration at a fast pace due to RPI requiring that we update the server OS to ensure proper security. We expect that this migration will take one day to complete. If it looks like the…
User Moor found a 78-digit prime factor of an Cunningham number using ECM. This is the largest ECM factor found this year, and the 4th largest for all times (and the largest found by yoyo@home).
Hi, during the holiday one disk of the server suddenly died, so it gets unavailable. Unfortunately I come back from holiday a week later, so all workunits and credits were already time out at that time. Disk died on 20 Aug during the day. The DB is the one of 8:00 as it from a clean backup (all WU and result where not touched from the disk damages, however some WU may be missed into the DB for credits, but not for the results collected). As the server were using an old SO that soon will go out…
Dear volunteers, The IT department has notified us that tomorrow, starting at 3:00 p.m. (CEST), maintenance work will be carried out on the university network. It is possible that from that moment on there will be problems accessing DENIS. Sorry for any inconvenience this may cause. Best, Jesús. ======================================== Estimados voluntarios: El departamento de Sistemas de Información nos ha avisado de que mañana, a partir de las 15:00 (CEST), se realizarán trabajos de…
hi, from tomorrow I will be on holiday for max 15 days without server access, so be sure to add a backup Boinc project in case of server problem.
Dear volunteers, We are approaching the month of August in which the university rests for vacations. While we may not stop completely, the number of tasks available this month will be fewer. Our attention to the state of the server will be reduced, so we do not want to take the risk of saturating it. Between the 20th to 28th the stop of new tasks will be total, resuming normal activity from the 29th or 30th. I take this opportunity to tell you that the different variations of the optimization…
In the BOINC project Gerasim@Home, one of my projects "Symmetric Tuples from Sequential Primes" is launched. https://gerasim.boinc.ru/news/news.aspx?id=131 Please participate in the "Get Symmetrical Tuples" Application!
Hey Everyone, I'll be shutting the server down for about an hour or two tomorrow at noon EDT (4 PM UTC) to take care of the loads of WUs stuck waiting for validation. They are from leftover Separation WUs trickling in after the project was shut off. Unfortunately I do not think that credit will be given out for these stuck WUs, as they were turned in after the project was shut down, and the validator is not running to give people credit. N-body WUs will not be affected by this, and all credit…
Dear volunteers, I am writing to update you on how the project is going and the results we are obtaining. First of all, the optimization of the new model we are developing has already finished (the first one we released). Unfortunately the results have not been as expected. The optimization has worked very well and many markers have been improved, but one of the model issues that we are trying to fix has reappeared after the optimization. We think we understand where the problem is coming from…
User ccurtis0 found a 73-digit prime factor of an XYYXF number using ECM. This is another entry into the ECMNET top 10 list for this year!
Hello everyone, Thanks for your discussion on the other thread (https://milkyway.cs.rpi.edu/milkyway/forum_thread.php?id=5007). Based on your input we have decided to turn off Separation this Tuesday. N-body will still be running, and we appreciate anyone who wants to help crunch work for that application! I am not able to give you an exact time estimate because it's not clear exactly how long it will take to properly shut things down; however, I expect it to be sometime around noon EDT (1600…
Dear Volunteers, We are beginning to sunset the Separation project (note that this is different from the N-Body project, which still needs your help!!!). Thanks to your computational contributions, we have completed the goals that we set out to accomplish with this the project, so we are going to shut down the Separation project in the near future. We are planning on submitting a paper containing the final results of the Separation project to an academic journal in the near future. It is…
Hello everyone, We will be running server maintenance on June 1st, 2023 at 11:30 AM EDT. Maintenance should be done by the end of the day. An announcement will be made on this thread when maintenance is over. Thanks, Kevin
The NFS@Home project will be offline much of the day on Saturday, May 27, due to campus IT maintenance and testing. All access should be restored by 8pm PDT. Greg Childers
User Favebook found a 77-digit prime factor of an Homogeneous Cunningham number using ECM. This is by far the largest factor found anywhere by ECM this year, and is the 4th largest ever. Very exciting!This was a very lucky find (about a 1 in 28.3 million chance for a single curve).
Hello everyone, RPI is conducting their annual CII power maintenance between May 8th and May 10th. As a precaution, we will need to shutdown the server during this time. We will have the server back up and running as soon as possible. Thank you, Kevin
Dear volunteers, We update you on the status of the project and how the simulations are going. In recent weeks the search algorithm has been improving the model very little. This indicates us that the optimization is close to be finished. Once this is complete we will pass to the validation phase which we will be done outside of DENIS (DENIS is not yet prepare for the required simulations). The improvement obtained is very considerable (you can see the graph with the evolution of the error…
Dear volunteers, Allow me a brief message to update you on how the results are going after 15 more days of simulation. 5 iterations of the algorithm have already been completed. Of the 100 markers that we are using, 89 have already been achieved in the normal range (initially only 77 were). On the other hand, the distance between the average experimental behavior and the model has been reduced by 56.84%. Several parameters of the algorithm indicate that there is still room for improvement. We…
Hello everyone, The following are the new runs for N-Body: de_nbody_02_27_2023_v182_pal5__data__1 de_nbody_02_27_2023_v182_pal5__data__2 de_nbody_02_27_2023_v182_pal5__data__3 These are our first runs of Palomar 5 with data from SDSS DR17. Please let me know if there are any issues with these new runs. Thanks, Kevin
Dear volunteers, The Science Commons Initiative has created a store to sell merchandising from BOINC projects to help fund the development of BOINC and the projects as well. We have given them permission so you can find products with the DENIS logo. 50% of the profits on these products will go to develop BOINC and the other 50% will be donated to support DENIS. You can see them at https://www.redbubble.com/es/shop/ap/138889661 However, if you have any questions about the products or anything…
Dear volunteers, We have good news! After processing the results of the first iteration, we have found a combination of model parameters that improves the behavior of the model compared to the initial one. In the original version, of the 100 markers that we are using, 77 were in the experimental range: now there are 80. On the other hand, the distance between the model and the average experimental behavior has been reduced by almost 30%. The values of several of the parameters that have been…
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