Function of a cryptic pocket
One of the Bowman lab’s major foci is on finding and targeting cryptic pockets. Cryptic pockets are absent in experimentally derived structures of what a protein typically looks like but open up due…
Advertisement
We understand ads are no fun, but they are what makes Gridcoinstats possible.
No ad to show here right now. We understand ads are no fun, but they are what makes Gridcoinstats possible.
The ads are blocked in your browser. We understand ads are no fun, but they are what makes Gridcoinstats possible.
Advertisement
We understand ads are no fun, but they are what makes Gridcoinstats possible.
No ad to show here right now. We understand ads are no fun, but they are what makes Gridcoinstats possible.
The ads are blocked in your browser. We understand ads are no fun, but they are what makes Gridcoinstats possible.
News
426 itemsNews of the research projects that Gridcoin pays for and of the Gridcoin releases, newest first. Press releases that companies pay to publish here are in the list too, marked as sponsored: Gridcoinstats does not write them and does not stand behind what they say.
Advertisement
We understand ads are no fun, but they are what makes Gridcoinstats possible.
No ad to show here right now. We understand ads are no fun, but they are what makes Gridcoinstats possible.
The ads are blocked in your browser. We understand ads are no fun, but they are what makes Gridcoinstats possible.
Advertisement
We understand ads are no fun, but they are what makes Gridcoinstats possible.
No ad to show here right now. We understand ads are no fun, but they are what makes Gridcoinstats possible.
The ads are blocked in your browser. We understand ads are no fun, but they are what makes Gridcoinstats possible.
The Bowman Lab Rig
Folding@home is an unmatched resource for running molecular dynamics simulations on a massive scale. The need for significant computational resources doesn't end with data generation though, as…
Project progress and summer period // Avance del proyecto y período estival
Dear volunteers, First of all, please excuse me because I wanted to send this message a week ago, but I was not able to do so. As you have seen these days, just like last year, we are entering the summer period, and the rate of sending simulations will be affected. We hope that it does not stop completely, but the sent tasks will be reduced. I take this opportunity to update the results of the last months: you have been optimizing one of the most used human ventricle models: the O'Hara and…
Improving protein design on Folding@home
The protein design field has been making great strides with the advent of new machine learning tools trained on large databases of protein structures and sequences. While designs coming from these…
Tackling Condensates
In recent years, scientists have identified a new type of compartment in cells, often called a condensate. These condensates form when weakly interacting proteins and RNA molecules segregate…
New software release!
We’re delighted to announce the full release of our new client software! We named this release “Bastet” after the Ancient Egyptian goddess associated with protection from disease. You can download…
Connecting with single molecule experiments
Our new work shows how to predict the results of single molecule experiments from large simulations, like those performed on Folding@home. Showing that simulations are consistent with experiments is…
Towards physics-based precision medicine
The goal of precision medicine is to utilize our knowledge of the molecular causes of disease to better diagnose and treat patients. In the precision medicine framework, diseases are subdivided by…
Electrical work 3
I just being informed now that tomorrow 29/05/2024 in my area there will be another electrical power off from 9:00 to 16:00!!!! This means that battery power supply cannot handle 7 hours of power failure, so I need to program that the server shot down automatically before 9:00 to preserve it. It need to be manually power on and this could be done at 19:00. Sorry for the problems. Thanks
BOINC Pentathlon - Thank you!
Thank you to all the BOINC Pentathlon participants who devoted their time and computing power to NFS@Home, and to SETI.Germany for organizing this event. We look forward to next time!
How does ApoE cause Alzheimer’s disease?
A number of active projects on Folding@home right now aim to understand how different forms of the protein apolipoprotein E (ApoE) determine one’s risk of developing Alzheimer’s disease. Alzheimer’s…
Electrical work 2
It seems that in my area electrical works are every month! On 16/05/2024 from 9:00 to 13:00 there is no electrical power in the area again, so no connection to server (power supply should be able to carry the 4h of power off and still run the server, but without connection to internet). Thanks
BOINC Pentathlon
Welcome BOINC Pentathlon participants. NFS@Home has been chosen for the Javelin Throw discipline starting May 10 at midnight UTC.
Some issues
I just see today that the OS update of some days ago has stopped something in connection. Now I reboot all to be sure new kernel were loaded. Actually log seems good, so I hope that the Boinc activity is restored good. Thanks
AlphaFold opens new opportunities for Folding@home
Folding@home has long sought to understand how proteins self-assemble, or fold, into their functional structures and what the functional implications of dynamics within the context of a folded…
Electrical work
On Thusday 23/4/2024 there are planned some electrical works in my area from 9:00 to 13:30 with power that probably will be tuned off too. So the server could be not reachable during that times due to loss of internet connection.
New Folding@home software in beta
The beta release of our new client software is going well. Thanks to everyone who has tried it out and given us feedback! If you haven't already, you can download the software here . This new client…
Lightning bolt
There was a lightning bolt on 1/4/2024 in the night that damage (e.g. they broke) many electrical devices in the area (1Km^2). Internet connection were restored only in the morning (as provider is at 200m distance of the server and it was damaged too). Even if the server is behind a power supply, it get in non operational state (e.g the data disk was disconnected), maybe due to the heavy electrical current it passes onto the battery power supply. Every disk of the server were un-mount from it…
Hard drive space crisis solved // Crisis de espacio en el disco duro resuelta
Dear volunteers, This weekend we have broken a new record for computing Teraflops (since we are in this new stage of the project). This is thanks to the pace of sending results that you have been doing in recent days and being more stable in the generation of work packages. Although we were monitoring it, the coincidence of this peak with the database backup on the weekend has caused the hard drive to become saturated sooner than expected. We have been working since Monday on moving data out…
Project status update // Actualización del estado del proyecto
Dear volunteers, I am writing to update you on how the different experiments we had launched have been going and the next steps we will take. On the one hand, we have finished (at least temporarily) the optimization of our model. As we had already told you, with the results that you have sent us, we managed to greatly improve how our model represented different physiological markers, but a problem that we thought we had solved had reappeared. We have tried different options but it reappeared…
And we're back!
The NFS@Home server was unexpectedly caught up in a campus network reorganization. That knocked us offline for a bit over a day. There may be brief outages over the next few days as we get everything settled again, but we are mostly back up with a new IP address. We apologize for the inconvenience. Edit: The site came back up in the US on Friday afternoon PST, but because of a misconfigured firewall it wasn't available worldwide until Saturday afternoon. Again, we apologize for the issues.
New K-Tuple competition
With the new year we organized a new K-Tuple competition: https://primesmagicgames.altervista.org/wp/primes-k-tuple-2/ The competition will last 3 months and is for finding new result about some k-tuple open problems (there are 7 tasks). Unless this Boinc project were all contribute to find solutions in latin squares field donating CPU power, the competition is for people that like to code programs and experiment with mathematics to find new solution by them-self. For this project instead, the…
Admin Updates
Hello everyone, This thread will be used as a place for project admins to post updates. If you have a comment or a question, you should post those in the appropriate threads. There is also an Admin Updates Discussion thread for further discussion on the updates. Thank you, Kevin
Admin Updates Discussion
Hello everyone, This thread will be used to discuss posts made in Admin Updates. Thanks, Kevin