This page shows information regarding BOINC projects on the Gridcoin Network. A project on the whitelist are rewarded for the share of work within that project on the Gridcoin Team. A project can be voted in or out at any given time by the community via the polls.

Please refer to the Gridcoin Projects Forum for help.

Team users that still does work, and could receive a reward for it, but has not advertised their precesence on the network with a Beacon are presented as Team Users w/o Beacon.

Team Users Total:

24068

Team Users w/ Magnitude:

952

Team Users w/o Beacon:

4398

Superblock Last:

2038374

Superblock Age:

11 hours, 50 minutes, 47 seconds ago

Included Projects:

18

Excluded Projects:

1

Past Projects:

44
Below list houses all availbale projects that gives rewards on the Gridcoin Network. Your reward are based on how much work you do, compared to how much work the team has done on each individual project. Each Project rewards equally much regardles of the amount of users. A Project with low participation may give a higher reward.

A Project needs to supply Gridcoin users with a constant supply of Work Units (WUs), failure to do so may result in delisting of the Project after a poll. Make sure you check that your current projects are on this list to get rewards.

The "Excluded Projects" list are projects that has failed to be inclueded in the latest superblock, rewards will not be generated for these projects until they are inclueded again. This may happen because the project servers are down or it was voted out by the community. Please refer to the Gridcoin Projects Forum for more details.

The "Past Projects" list are projects that has been exluded for longer than 2 weeks.
Some fields in the below table are hidden due to narrow screen. Turn your screen to display all columns.
Project Name WUs

Available

WUs

In Progress

Team

RAC

Team

Users

YafuWebpage 462 1,449 1,876,807 829
Odlk1Webpage 217,095 156,959 1,219,703 916
SRBaseWebpage -1 -1 11,034,617 773
TN-GridWebpage -1 -1 1,438,974 937
GpugridWebpage 78,436 6,996 57,173,364 4446
Nfs@homeWebpage 589,805 77,920 3,538,547 1919
Yoyo@homeWebpage 18,516 40,160 1,981,722 2263
Rosetta@homeWebpage -1 -1 9,037,262 7850
Einstein@homeWebpage 23,454,507 5143
Milkyway@homeWebpage 10,481 991,667 38,750,824 5830
Universe@homeWebpage 617,988 227,321 15,908,594 2610
Asteroids@homeWebpage 0 228,178 8,703,915 5831
Cosmology@homeWebpage 2,733 77,257 1,410,158 3067
Amicable_NumbersWebpage 3,725 27,856 21,539,106 1882
Lhc@home_classicWebpage 5,064 37,159 560,819 4389
Numberfields@homeWebpage -1 -1 2,572,633 1649
Collatz_conjectureWebpage 753 267,394 476,783,135 2182
World_Community_GridWebpage -1 -1 12,979,350 1
Project Name Last Seen
NeuralNetworkWebpage 2020-09-11
Project Name Last Seen
Albert@homeWebpage 2016-06-12
Amicable NumbersWebpage 2020-01-05
Atlas@homeWebpage 2017-04-04
Bitcoin UtopiaWebpage 2016-05-25
BurpWebpage 2017-01-03
Cas@homeWebpage 2016-06-12
Citizen Science GridWebpage 2019-05-13
Citizen_Science_GridWebpage 2019-05-29
Climate PredictionWebpage 2019-01-20
Climateprediction.netWebpage 2015-11-10
Collatz ConjectureWebpage 2020-01-05
Constellation 2015-07-28
Convector 2015-07-17
Denis@homeWebpage 2016-07-06
DhepWebpage 2019-08-22
Distributed Data MiningWebpage 2015-11-10
DistributeddataminingWebpage 2017-10-12
Drugdiscovery@homeWebpage 2018-02-26
Edges@home 2015-07-28
Enigma@homeWebpage 2019-05-31
Find@homeWebpage 2015-12-02
Gridcoin Finance 2016-08-27
Leiden ClassicalWebpage 2017-10-12
Lhc@homeWebpage 2015-11-10
Lhc@home ClassicWebpage 2020-01-05
Malaria ControlWebpage 2016-02-11
Malariacontrol.net 2015-11-10
Mindmodeling@homeWebpage 2016-11-27
Moo! WrapperWebpage 2015-11-10
MoowrapWebpage 2019-01-20
Poem@homeWebpage 2016-11-02
PrimaboincaWebpage 2015-07-17
PrimegridWebpage 2018-10-12
Quake Catcher NetworkWebpage 2015-07-17
Sat@homeWebpage 2016-11-27
Seti@homeWebpage 2020-04-04
Seti@home Beta 2015-07-30
SourcefinderWebpage 2018-02-28
Sztaki Desktop GridWebpage 2017-10-12
Theskynet PogsWebpage 2018-05-06
Vgtu Project@homeWebpage 2019-01-06
VlhcathomeWebpage 2017-02-02
World Community GridWebpage 2020-01-05
Wuprop@home 2016-08-03
More BOINC related news and updates can be read under each project. Below are the last 12 updates from all active projects.

Tenth anniversary of the first Einstein@Home discovery

Ten years ago, Einstein@Home published its first astronomical discovery. The radio pulsar J2007+2722 was found in July 2010 with our radio pulsar search, analyzing data from the Arecibo Radio Telescope. The discovery [Link] appeared in print on 10 September 2010. A [Link] more detailed article about the discovery was published later.[Link] read more

By einstein@home at 2020-09-10

New paper: Small Molecule Modulation of Intrinsically Disordered Proteins Using Molecular Dynamics Simulations.

Another great GPUGRID-based work: studying the possible modulation of intrinsically disordered proteins through drugs. Herrera-Nieto P, Pérez A, De Fabritiis G, Small Molecule Modulation of Intrinsically Disordered Proteins Using Molecular Dynamics Simulations. Journal of chemical information and modeling 2020. doi:10.1021/acs.jcim.0c00381 The corresponding badge is labeled "Herrera-Nieto, JCIM 2020". The extreme dynamic behavior of intrinsically disordered proteins hinders the development of drug-like compounds capable of modulating them. There are several examples of small molecules that specifically interact with disordered peptides. However, their mechanisms of action are still not well understood. Here, we use extensive molecular dynamics simulations combined with adaptive sampling algorithms to perform free ligand binding studies in the context of intrinsically disordered proteins. We tested this approach in the system composed by the D2 sub-domain of the disordered protein p27 and the small molecule SJ403. The results show several protein–ligand bound states characterized by the establishment of a loosely oriented interaction mediated by a limited number of contacts between the ligand and critical residues of p27. Finally, protein conformations in the bound state are likely to be explored by the isolated protein too, therefore supporting a model where the addition of the small molecule restricts the available conformational space.

By gpugrid at 2020-09-09

Server unreachable (2020-09-09, from 05:30 to 08:00 CEST)

Wednesday 09/09, from 05:30 to 08:00 CEST, the IT services of UniTrento will not be available because of a planned IT maintenance. The TN-Grid server (hosted by UniTrento) will probably be not reachable during this period.

By tn-grid at 2020-09-08

BOINC database downtime

The LHC@home database will be down for a while this morning, due to a network interruption in the CERN data centre. Hence scheduler requests and uploads will fail for a while. Sorry for the trouble and happy crunching.

By lhc@home_classic at 2020-09-07

Two new apps launched

Two new apps have been launched, lasievee_small and lasievef_small. As the numbers we factor become larger, the lasieved app has largely become inadequate while the lasievee app queue has grown very long. In an attempt to compensate, job memory use and runtime has crept upward to stretch the capability of the apps. To alleviate these issues, these new apps will provide additional flexibility to choose the app most appropriate to the size of the number being factored while keeping memory use and runtime more reasonable. If you have modified your project preferences to run only specific applications, you may want to adjust your settings to enable these new apps. Thanks for your contributions to NFS@Home!

By nfs@home at 2020-09-03

2020 BOINC Workshop - Call for Volunteers

In light of the cancelation of the 2020 BOINC Workshop in Marburg, Germany, there will be a virtual celebration of BOINC projects, development, and community. As with all things BOINC, your help -- the BOINC community -- is needed to produce the event. Learn more below and at [Link] http://www.boincworkshop.org/.

By einstein@home at 2020-09-03

New paper: Computational and experimental characterization of NF023, a candidate anticancer compound inhibiting…

Here we studied a possible mode of action of NF023, a molecule which disrupts some protein-protein interactions (cIAP-TRAF) misregulated in cancer. The molecule is very charged and flexible, so classical docking studies aren't up to a full modeling... but large-scale MD powered by GPUGRID is. Cossu F, Sorrentino L, Fagnani E, Zaffaroni M, Milani M, Giorgino T, Mastrangelo E. Computational and experimental characterization of NF023, a candidate anticancer compound inhibiting cIAP2/TRAF2 assembly. J Chem Inf Model. 2020 Aug 21 [Link] doi:10.1021/acs.jcim.0c00518 Protein-protein interactions are the basis of many important physiological processes, and are currently promising, yet difficult, targets for drug discovery. In this context, inhibitors of apoptosis (IAPs)-mediated interactions are pivotal for cancer cell survival; the interaction of the BIR1 domain of cIAP2 with TRAF2 was shown to lead the recruitment of cIAPs to the TNF-receptor, promoting the activation of NF-κB survival pathway. In this work, using a combined in silico-in vitro approach we identified a drug-like molecule, NF023, able to disrupt cIAP2 interaction with TRAF2. We demonstrated in vitro its ability to interfere with the assembly of the cIAP2-BIR1/TRAF2 complex and performed a thorough characterization of the compound’s mode of action through 248 parallel unbiased molecular dynamics simulations of 300 ns (totaling almost 75 µs of all-atom sampling), which identified multiple binding modes to the BIR1 domain of cIAP2 via cl...

By gpugrid at 2020-09-02

Science pages updated

Should now reflect the list of papers and badges. Some data, e.g. images, is missing.

By gpugrid at 2020-08-31

New paper: Characterization of partially ordered states in the intrinsically disordered N-terminal domain of p53 using millisecond molecular dynamics simulations

The latest scientific publication obtained with your support and computation is here: Herrera-Nieto, P., Pérez, A. & De Fabritiis, G. Characterization of partially ordered states in the intrinsically disordered N-terminal domain of p53 using millisecond molecular dynamics simulations. [Link] Sci Rep 10, 12402 (2020). It investigates an open and difficult problem in biology, namely the structure-function relationship of intrinsically disordered proteins (IDP). IDP proteins are involved in many regulatory processes, and yet are difficult to study both experimentally and computationally. The amount of power provided by GPUGRID volunteers came to the rescue, enabling very extensive sampling of p53, an exemplary IDP involved in oncogenic processes. The exploration of intrinsically disordered proteins in isolation is a crucial step to understand their complex dynamical behavior. In particular, the emergence of partially ordered states has not been explored in depth. The experimental characterization of such partially ordered states remains elusive due to their transient nature. Molecular dynamics mitigates this limitation thanks to its capability to explore biologically relevant timescales while retaining atomistic resolution. Here, millisecond unbiased molecular dynamics simulations were performed in the exemplar N-terminal region of p53. In combination with state-of-the-art Markov state models, simulations revealed the existence of several partially ordered states accounting for ∼ 40% of the ...

By gpugrid at 2020-08-26

Continued NBody Runs (07/29/2020)

Hey everyone, The last set of NBody runs have just converged beautifully. We are currently working on writing the paper to publish these results. In the meantime, we will be replacing these runs with another set: -de_nbody_07_29_2020_v176_40k__data__4 -de_nbody_07_29_2020_v176_40k__data__5 -de_nbody_07_29_2020_v176_40k__data__6 Thank you all so much for your support. We would not be able to write this paper without your continued assistance. -Eric

By milkyway@home at 2020-08-17

Enhancing ECM range

I'm enhancing the ecm search range for B1=43e6 up to 2000 digits. Some test workunits are already send out with the name ecm_es_*test* and a short deadline of 1 day. Together with this the credit formula was changed.

By yoyo@home at 2020-07-31

New Runs for MilkyWay@home Nbody Simulations (07/29/2020)

Hey everyone, I just wanted to let everyone know that new Nbody runs have been put up on MW@home. The last set of runs started converging nicely, so we are confident this next set of runs will converge as well. The names of these runs are: -de_nbody_07_29_2020_v176_40k__data__1 -de_nbody_07_29_2020_v176_40k__data__2 -de_nbody_07_29_2020_v176_40k__data__3 Please let us know if you have any trouble with these runs. Thank you all for your continued support. -Eric

By milkyway@home at 2020-07-30


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